Chronic kidney disease and comorbid diseases of gastrointestinal tract

Nowadays the patient more often has a comorbid pathology. The combinations of two or chronic diseases, which are either pathologically interlaced exist simultaneously, may worsen case each individual disease. Kidney diseases associated with gastrointestinal disorders, cardiovascular and endocrine because same immunological features etiology pathogenesis. Chronic kidney disease (CKD) requires correction lifestyle implementation control over physical development in children from first stages CKD C4-C5 leads to unbalance homeostasis increased level toxic substances blood, that is why doctors can see changes different organs systems especially tract. urinary system tract have common plan structure, functioning regulation. It determines general mechanisms There direct correlation between stage damage system. This article covers pathophysiological digestive advanced CKD. Special attention paid microbiota In turn, it affects systemic inflammation, an aggravating factor course its progression. emphasis made on involvement varying degrees C4-C5.